Visit Adherence of Mild to Moderate Psoriasis Patients: A Mobile-Based Randomized Study

Yi Zhao; Gang Wang; Wenqiong Ni; Zhiqiang Song; Kun Chen; Chunlei Zhang; Shoumin Zhang; Yangfeng Ding; Min Zheng; Yulin Shi; Zhimiao Lin; Xiaomin Liu; Xiaofei Zhang; Qintian Zhou; Kazi Deluwar Ahmed

doi:10.2147/PPA.S277103

Visit Adherence of Mild to Moderate Psoriasis Patients: A Mobile-Based Randomized Study

Patient Prefer Adherence. 2021 Jan 5:14:2551-2557. doi: 10.2147/PPA.S277103. eCollection 2020.

Authors

Yi Zhao¹, Gang Wang², Wenqiong Ni³, Zhiqiang Song⁴, Kun Chen⁵, Chunlei Zhang⁶, Shoumin Zhang⁷, Yangfeng Ding⁸, Min Zheng⁹, Yulin Shi¹⁰, Zhimiao Lin¹¹, Xiaomin Liu¹², Xiaofei Zhang¹³, Qintian Zhou¹⁴, Kazi Deluwar Ahmed¹⁴

Affiliations

¹ Department of Dermatology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, People's Republic of China.
² Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China.
³ Department of Dermatology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, People's Republic of China.
⁴ Department of Dermatology, Southwest Hospital, The Third Military Medical University, Chongqing, People's Republic of China.
⁵ Institute of Dermatology, Chinese Academy of Medical Science and Peking Union Medical College, Nanjing, People's Republic of China.
⁶ Department of Dermatology, Peking University Third Hospital, Beijing, People's Republic of China.
⁷ Department of Dermatology, Henan Provincial People's Hospital, Zhengzhou 450003, People's Republic of China.
⁸ Department of Dermatology, Shanghai Skin Disease Hospital, Shanghai, People's Republic of China.
⁹ Department of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
¹⁰ Department of Dermatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine; Institute of Psoriasis, Tongji University School of Medicine, Shanghai, People's Republic of China.
¹¹ Department of Dermatology and Venereology, Peking University First Hospital, Beijing, People's Republic of China.
¹² Department of Dermatology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, People's Republic of China.
¹³ Department of Clinical Epidemiology and Biostatistics, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, People's Republic of China.
¹⁴ Scientific Affairs and MSL Department, LEOPharma China, Shanghai, People's Republic of China.

Abstract

Objective: We aimed to prospectively evaluate the visit adherence in mild to moderate psoriasis patients.

Methods: Plaque psoriasis patients aged 18 or above who were prescribed with a two-component formula ointment were eligible for the study. The patients were randomly assigned to group A or B, and received management with or without planned patient-doctor communication via a mobile platform. The outpatient visit was scheduled at week 2, 8, 16, 28, 48, and 52. Visit adherence was evaluated as the visit rate of the patients.

Results: Two hundred twenty-one patients were included. Generally, the visit adherence dropped over time during follow-up. The visit rates in group A were 5.2-15.7% through the 52 weeks, and similar rates were found in group B (7.5-17.0%, vs group A, P > 0.05). A negative binomial regression model showed that older age and higher BSA were correlated with more frequent visits.

Conclusion: The visit adherence of mild to moderate psoriasis patients was very low in China. Proactive inquiries of the doctors via the mobile platform failed to improve the visit adherence of the patients.

Keywords: psoriasis; topical treatment; visit adherence.

Grants and funding

This research is sponsored by LEO Pharma. The sponsor participated in study design and study conduction in cooperation with the investigators, while not involved in data collection, analyses or interpretation.