We examined a 16-year-old boy with a remarkable decrease in vision OS. Typical lesions of acute retinal pigment epitheliitis (Krill's disease) were not present in the macula but were diffuse in the midperiphery. Angiographic findings were similar to those in Krill's disease. The left fundus returned to normal two weeks later, but ten months passed before electro-oculography, light sensitivity, and dark adaptation were normal. Thus, there may be two types of acute retinal pigment epitheliitis: one is Krill's disease, and the other is a vast disturbance in the retinal pigment epithelium.