Clinical Features of Venous Thromboembolism in Patients With Coronavirus Disease 2019 (COVID-19) in Japan - A Case Series Study

Circ J. 2021 Feb 25;85(3):309-313. doi: 10.1253/circj.CJ-20-1302. Epub 2021 Jan 20.

Abstract

Background: Suspicion that the coronavirus disease 2019 (COVID-19) caused venous thromboembolism (VTE).

Methods and results: We conducted a case series study of 5 VTE patients with COVID-19 in Japan. The median body mass index was 27.7 kg/m2, and all patients required mechanical ventilation during hospitalization. Patients were diagnosed as VTE in the intensive care unit (ICU), general ward, and outpatient ward.

Conclusions: The current case series study revealed some clinical features of VTE patients with COVID-19 in Japan, including obese patients and those requiring mechanical ventilation during hospitalization, who should be followed closely for VTE, even after leaving the ICU.

Keywords: Coronavirus disease 2019 (COVID-19); Pulmonary embolism; Venous thromboembolism.

MeSH terms

  • Adult
  • Aged
  • COVID-19 / blood
  • COVID-19 / complications*
  • Fibrin Fibrinogen Degradation Products / analysis
  • Humans
  • Intensive Care Units
  • Japan / epidemiology
  • Male
  • Middle Aged
  • Obesity / complications
  • Oxygen / blood
  • Patients' Rooms
  • Pulmonary Embolism / epidemiology
  • Pulmonary Embolism / etiology
  • Respiration, Artificial
  • Respiratory Distress Syndrome / diagnostic imaging
  • Respiratory Distress Syndrome / etiology
  • Respiratory Distress Syndrome / therapy
  • SARS-CoV-2*
  • Thrombophilia / blood
  • Thrombophilia / etiology
  • Tomography, X-Ray Computed
  • Venous Thromboembolism / epidemiology
  • Venous Thromboembolism / etiology*
  • Venous Thrombosis / epidemiology
  • Venous Thrombosis / etiology

Substances

  • Fibrin Fibrinogen Degradation Products
  • fibrin fragment D
  • Oxygen