Rhabdomyosarcoma in Roberts syndrome

S L Wenger; J Blatt; M W Steele; D A Lloyd; M Bellinger; C K Phebus; M Horn; R Jaffe

doi:10.1016/0165-4608(88)90230-0

Rhabdomyosarcoma in Roberts syndrome

Cancer Genet Cytogenet. 1988 Apr;31(2):285-9. doi: 10.1016/0165-4608(88)90230-0.

Authors

S L Wenger¹, J Blatt, M W Steele, D A Lloyd, M Bellinger, C K Phebus, M Horn, R Jaffe

Affiliation

¹ Department of Medical Genetics, Children's Hospital of Pittsburgh, University of Pittsburgh, School of Medicine 15213-3417.

PMID: 3349442
DOI: 10.1016/0165-4608(88)90230-0

Abstract

A 23-month-old child diagnosed as having Roberts syndrome, born to consanguineous parents, developed a sarcoma botryoides. Cytogenetic evaluation of peripheral blood lymphocytes and tumor cells showed premature centromere separation, which is characteristic of Roberts syndrome.

Publication types

Case Reports

MeSH terms

Abnormalities, Multiple*
Child, Preschool
Female
Humans
Karyotyping
Rhabdomyosarcoma / complications
Rhabdomyosarcoma / genetics*
Rhabdomyosarcoma / pathology
Syndrome
Urinary Bladder Neoplasms / complications
Urinary Bladder Neoplasms / genetics*
Urinary Bladder Neoplasms / pathology