An international retrospective study for tolerability of 6-mercaptopurine on NUDT15 bi-allelic variants in children with acute lymphoblastic leukemia

Affiliations

• ¹ Division of Medicinal Safety Science, National Institute of Health Sciences, Kawasaki.
• ² VIVA-NUS Centre of Translational Research in Acute Leukaemia (Molecular), Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore.
• ³ Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN.
• ⁴ Hong Kong Children's Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, Special Administrative Region.
• ⁵ Department of Pediatrics, Hirosaki University Graduate School of Medicine, Hirosaki.
• ⁶ Department of Hematology/Oncology, Saitama Children's Medical Center, Saitama.
• ⁷ Hematology/Oncology Division, Department of Pediatrics Faculty of Medicine, Siriraj Hospital Mahidol University.
• ⁸ Department of Hematology and Oncology, Guangzhou Women and Children's Medical Center.
• ⁹ Division of Pediatric Hematology-Oncology, Mackay Children's Hospital and Mackay Memorial Hospital, Taipei.
• ¹⁰ Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur.
• ¹¹ Department of Pediatrics, St. Luke's International Hospital, Tokyo.
• ¹² Department of Pediatrics, Juntendo University, School of Medicine, Tokyo.
• ¹³ Department of Pediatrics, St. Marianna University School of Medicine Hospital, Kawasaki.
• ¹⁴ Department of Hematology and Oncology, Miyagi Children's Hospital, Sendai.
• ¹⁵ Department of Pediatrics, Nippon Medical School, Tokyo.
• ¹⁶ Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo.
• ¹⁷ Department of Hematology/Oncology, Chiba Children's Hospital, Chiba.
• ¹⁸ Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba.
• ¹⁹ Department of Pediatrics, Tokyo Medical and Dental University, Tokyo.
• ²⁰ Department of Pediatrics, Toho University School of Medicine, Tokyo.
• ²¹ Department of Pediatrics, Mie University, Tsu, Mie.
• ²² Department of Pediatrics, Hokkaido University Graduate School of Medicine, Sapporo.
• ²³ Department of Transplantation and Cell Therapy, Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan; Department of Pediatric Hematology and Oncology Research, National Center for Child Health and Development, Tokyo, Japan; Department of Pediatrics, the University of Tokyo, Tokyo. [email protected].