Spinal Cord Infarction in a Patient with Immune Thrombocytopenic Purpura

Kenta Orimo; Mizuki Ogura; Keiko Hatano; Naoko Saito-Sato; Hideki Nakayama; Tadao Ishida; Hideji Hashida

doi:10.1016/j.jstrokecerebrovasdis.2021.105637

Spinal Cord Infarction in a Patient with Immune Thrombocytopenic Purpura

J Stroke Cerebrovasc Dis. 2021 Apr;30(4):105637. doi: 10.1016/j.jstrokecerebrovasdis.2021.105637. Epub 2021 Jan 25.

Authors

Kenta Orimo¹, Mizuki Ogura², Keiko Hatano³, Naoko Saito-Sato⁴, Hideki Nakayama⁵, Tadao Ishida⁶, Hideji Hashida⁷

Affiliations

¹ Department of Neurology, Japanese Red Cross Medical Center, Tokyo, Japan. Electronic address: [email protected].
² Department of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan. Electronic address: [email protected].
³ Department of Neurology, Japanese Red Cross Medical Center, Tokyo, Japan. Electronic address: [email protected].
⁴ Department of Neurology, Japanese Red Cross Medical Center, Tokyo, Japan. Electronic address: [email protected].
⁵ Department of Neurology, Japanese Red Cross Medical Center, Tokyo, Japan. Electronic address: [email protected].
⁶ Department of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan. Electronic address: [email protected].
⁷ Department of Neurology, Japanese Red Cross Medical Center, Tokyo, Japan. Electronic address: [email protected].

PMID: 33508727
DOI: 10.1016/j.jstrokecerebrovasdis.2021.105637

Abstract

Immune thrombocytopenic purpura (ITP) can increase the risk of not only hemorrhagic incidents but also thrombotic events. Although several patients with ITP who developed cerebral infarction have been reported, concurrence of spinal cord infarction and ITP has not been reported. We report the case of a female patient who developed spinal cord infarction during the exacerbation of her ITP. This case suggests a possible association between spinal cord infarction and ITP, which can cause paradoxical thrombosis.

Keywords: Idiopathic thrombocytopenic purpura; Paradoxical thrombosis; Spinal cord ischemia; Thrombocytopenia.

Publication types

Case Reports

MeSH terms

Aged
Disease Progression
Female
Glucocorticoids / therapeutic use
Hematologic Agents / therapeutic use
Humans
Immunosuppressive Agents / therapeutic use
Infarction / diagnostic imaging
Infarction / etiology*
Infarction / rehabilitation
Purpura, Thrombocytopenic, Idiopathic / complications*
Purpura, Thrombocytopenic, Idiopathic / diagnosis
Purpura, Thrombocytopenic, Idiopathic / drug therapy
Spinal Cord / blood supply*
Thrombosis / diagnostic imaging
Thrombosis / etiology*
Treatment Outcome

Substances

Glucocorticoids
Hematologic Agents
Immunosuppressive Agents