Whole-Transcriptome Profiling of Human Heart Tissues Reveals the Potential Novel Players and Regulatory Networks in Different Cardiomyopathy Subtypes of Heart Failure

Circ Genom Precis Med. 2021 Feb;14(1):e003142. doi: 10.1161/CIRCGEN.120.003142. Epub 2021 Feb 1.
No abstract available

Keywords: cardiomyopathies; gene expression; heart failure; phenotype; transcriptome.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Biomarkers / metabolism
  • Cardiomyopathies / complications
  • Cardiomyopathies / genetics
  • Cardiomyopathies / pathology*
  • Down-Regulation
  • Gene Expression Profiling / methods
  • Gene Regulatory Networks / genetics*
  • Heart Failure / etiology
  • Heart Failure / genetics
  • Heart Failure / pathology*
  • Heart Ventricles / metabolism*
  • Humans
  • Myocardium / metabolism
  • Phenotype
  • Receptor, Notch2 / genetics
  • Receptor, Notch2 / metabolism
  • Semaphorins / genetics
  • Semaphorins / metabolism
  • Signal Transduction / genetics
  • Transcriptome*
  • Up-Regulation

Substances

  • Biomarkers
  • NOTCH2 protein, human
  • Receptor, Notch2
  • Sema4c protein, human
  • Semaphorins