The impact of cardiovascular diseases on maternal deaths in the Nordic countries

Acta Obstet Gynecol Scand. 2021 Jul;100(7):1273-1279. doi: 10.1111/aogs.14104. Epub 2021 Feb 21.

Abstract

Introduction: Cardiovascular diseases have become increasingly important as a cause of maternal death in the Nordic countries. This is likely to be associated with a rising incidence of pregnant women with congenital and acquired cardiac diseases. Through audits, we aim to prevent future maternal deaths by identifying causes of death and suboptimal factors in the clinical management.

Material and methods: Maternal deaths in the Nordic countries from 2005 to 2017 were identified through linked registers. The national audit groups performed case assessments based on hospital records, classified the cause of death, and evaluated the standards of clinical care provided. Key messages were prepared to improve treatment.

Results: We identified 227 maternal deaths, giving a maternal mortality rate of 5.98 deaths per 100 000 live births. The most common cause of death was cardiovascular disease (n = 36 deaths). Aortic dissection/rupture, myocardial disease, and ischemic heart disease were the most common diagnoses. In nearly 60% of the cases, the disease was not recognized before death. In more than half of the deaths, substandard care was identified (59%). In 11 deaths (31%), improvements to care that may have made a difference to the outcome were identified.

Conclusions: Between 2005 and 2017, cardiovascular diseases were the most common causes of maternal deaths in the Nordic countries. There appears to be a clear potential for a further reduction in these maternal deaths. Increased awareness of cardiac symptoms in pregnant women seems warranted.

Keywords: audit; cardiovascular disease; cause of death; high-risk pregnancy; maternal mortality.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cardiovascular Diseases / mortality*
  • Cause of Death
  • Female
  • Humans
  • Maternal Death / statistics & numerical data*
  • Maternal Mortality
  • Population Surveillance
  • Pregnancy
  • Pregnancy Complications / mortality
  • Pregnancy Complications, Cardiovascular / mortality*
  • Registries*
  • Scandinavian and Nordic Countries