When cardiomyopathy, cancer, and COVID-19 collide: A case report

Breast J. 2021 Apr;27(4):384-386. doi: 10.1111/tbj.14182. Epub 2021 Feb 1.

Abstract

Malignancy has historically prohibited solid organ transplant; however, patients with effectively treated, favorable-risk cancers should not necessarily be eliminated as transplant candidates. These cases require careful review by a multidisciplinary team. Here, we report the case of a woman with end-stage heart failure undergoing heart transplant evaluation during the COVID pandemic who was found to have early-stage, hormone receptor-positive breast cancer. Given her favorable cancer-related prognosis, a multidisciplinary committee recommended lumpectomy, accelerated partial breast irradiation, and adjuvant aromatase inhibitor therapy for definitive treatment to allow for consideration of orthotopic heart transplant.

Keywords: COVID-19; breast cancer; cardiomyopathy; heart transplant.

Publication types

  • Case Reports

MeSH terms

  • Breast Neoplasms / complications*
  • Breast Neoplasms / surgery
  • COVID-19 / complications*
  • Cardiomyopathies / complications*
  • Female
  • Heart Failure / complications*
  • Heart Transplantation
  • Humans
  • Middle Aged
  • Pandemics