Quality of life in paediatrics with intractable epilepsy in a large paediatric university hospital in Riyadh, Saudi Arabia

Waleed A Altwaijri; Buthaina J Yahya; Lama B Alasmari; Rofan N Alsultan; Shoq M Alsuhaibani; Rawan M Alsemih; Afaf K Moukaddem

doi:10.4103/jfmpc.jfmpc_1172_20

Quality of life in paediatrics with intractable epilepsy in a large paediatric university hospital in Riyadh, Saudi Arabia

J Family Med Prim Care. 2020 Nov 30;9(11):5523-5536. doi: 10.4103/jfmpc.jfmpc_1172_20. eCollection 2020 Nov.

Authors

Waleed A Altwaijri¹, Buthaina J Yahya², Lama B Alasmari², Rofan N Alsultan², Shoq M Alsuhaibani², Rawan M Alsemih², Afaf K Moukaddem³

Affiliations

¹ Department of Pediatric Neurology, King Abdullah International Medical Research Center ( KAIMRC), Riyadh, Saudi Arabia.
² Department of College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
³ Department of Medical Education, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Abstract

Context: Epilepsy is said to be intractable when two or more trials of anticonvulsants fail to control the seizures. Literature suggests that intractable epilepsy carries a higher morbidity than controlled epilepsy in children and their caregivers.

Aims: The aim of this study is to assess the quality of life (QOL) in children with intractable epilepsy (IE) in KASCH, a tertiary care hospital in Riyadh, Saudi Arabia.

Settings and design: This is a cross-sectional study utilizing a self-administered questionnaire filled by caregivers of epileptic patients visiting the outpatient neurology clinics.

Methods and materials: The quality of life in childhood epilepsy (QOLCE-55) scale examined four domains of life: cognitive, emotional, social, and physical. The sample consisted of 59 parents whose children aged 4-14 of either sex.

Statistical analysis used: The collected data were analyzed by Statistical Package for the Social Sciences (SPSS) version 22.

Results: The mean age of children was 8.9 (SD = 2.9). The mean QOL was 52.8 (SD = 12.9), which reflected a poor QOL. Age was not related to the QOL. Gender was significantly associated with the total and social scores, (P = 0.04) (P = 0.001), respectively. Out of all comorbidities, global developmental delay (GDD) and encephalopathy were significantly associated with the QOL (P < 0.05).

Conclusions: Intractable epilepsy impacted all functioning domains of life rendering a poor QOL. Males have reported better QOL and social functioning compared to females. Children with GDD and encephalopathy showed lower well-being.

Keywords: Epilepsy; intractable; pediatric; quality of life.