Effects of centralized isolation vs. home isolation on psychological distress in patients with COVID-19

J Psychosom Res. 2021 Apr:143:110365. doi: 10.1016/j.jpsychores.2021.110365. Epub 2021 Jan 19.

Abstract

Objective: This study aimed to evaluate the impact of isolation form on the recovery of psychological distress in patients with coronavirus disease 2019 (COVID-19) after being discharged from hospital.

Methods: Baseline survey was conducted from February 10, 2020 to February 25, 2020 in patients with COVID-19 in a designated hospital on the discharge day. After discharge, patients were free to choose whether isolate in a centralized isolation site (i.e. designated hotel) or their own home for another two weeks. A follow-up survey was conducted at the end of the 2-week post-discharge isolation. Depression, anxiety as well as self-rated health were assessed at both time points using the 9-item patient health questionnaire, 7-item generalized anxiety disorder scale and self-rated health scores, respectively.

Results: Fifty centrally isolated and 45 home isolated patients completed both the baseline and the follow-up assessments. Significant effects of time and time by isolation form were found on depression and anxiety levels, with a significant decrease in depression and anxiety shown in home isolated but not in centrally isolated patients. Besides, a significant time effect was identified on self-rated health with significant improvement found in home isolated but not in centrally isolated patients.

Conclusions: Home isolation is superior to centralized isolation in the recovery of COVID-19-associated depression, anxiety as well as self-rated health. More attention needs to be paid to the psychological well-being of centrally isolated patients. A sustained and integrated rehabilitation plan is warranted for patients with COVID-19 to achieve both physical and psychological recovery.

Keywords: Anxiety; Coronavirus disease 2019; Depression; Isolation form; Self-rated health.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Aftercare
  • Anxiety / complications*
  • COVID-19 / psychology*
  • COVID-19 / therapy*
  • China / epidemiology
  • Continuity of Patient Care
  • Depression / complications*
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Patient Discharge*
  • Patient Health Questionnaire
  • Patient Isolation / psychology*
  • Psychological Distress*
  • Residence Characteristics
  • Stress, Psychological
  • Surveys and Questionnaires