NPM1-mutant acute myeloid leukemia relapsing as acute lymphoblastic leukemia with clonal persistence of IDH1 mutation

Leuk Lymphoma. 2021 Jul;62(7):1790-1792. doi: 10.1080/10428194.2021.1881510. Epub 2021 Feb 13.

Authors

Hari S Raman^{1

2}, Vignesh Shanmugam^{1

3}, Jingwei Li^{1

3}, David P Steensma^{1

4}, Annette S Kim^{1

3}, Marlise R Luskin^{1

4}

Affiliations

¹ Harvard Medical School, Boston, MA, USA.
² Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
³ Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.
⁴ Dana-Farber Cancer Institute, Boston, MA, USA.

PMID: 33586600
DOI: 10.1080/10428194.2021.1881510

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Female
Humans
Isocitrate Dehydrogenase / genetics
Leukemia, Myeloid, Acute* / diagnosis
Leukemia, Myeloid, Acute* / genetics
Middle Aged
Mutation
Nuclear Proteins / genetics
Nucleophosmin
Precursor Cell Lymphoblastic Leukemia-Lymphoma* / diagnosis
Precursor Cell Lymphoblastic Leukemia-Lymphoma* / genetics

Substances

NPM1 protein, human
Nuclear Proteins
Nucleophosmin
Isocitrate Dehydrogenase
IDH1 protein, human