Introduction and importance: Pericardial involvement due to gastric cancer is uncommon, especially when it is secondary to direct tumor infiltration. Its manifestation as cardiac tamponade is an exceptional situation that represents a challenge for the treating medical team.
Case presentation: a case of a patient with advanced gastric cancer with cardiopericardial infiltration, complicated with cardiac tamponade is reported. A narrative review of the diagnostic and therapeutic management was performed.
Clinical discussion: There are no well-established diagnostic and therapeutic algorithms.
Conclusions: It is such an exceptional entity that most of the available bibliography is based on case reports or expert opinions. It is a situation with a very bad prognosis.
Keywords: Cardiac tamponade; Case report; Pericardium; Stomach neoplasms.
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