Melaleuca alternifolia essential oil soap: a potential alternative for hand hygiene

Eur J Clin Microbiol Infect Dis. 2021 Jul;40(7):1517-1520. doi: 10.1007/s10096-021-04190-w. Epub 2021 Feb 26.

Abstract

This study aimed to compare the antimicrobial action of three soaps for hand hygiene (HH): 2.0% Tea Tree Oil (TTO); 0.5% triclosan; 2.0% chlorhexidine, and to explore the perception of healthcare professionals about TTO. Two-step study: a quantitative, to determine the logarithmic reduction of Escherichia coli K12 colony-forming units before and after HH of 15 volunteers and quali-quantitative, through interviews with 23 health professionals. All the three products demonstrated antimicrobial action (a log10 reduction factor of 4.18 for TTO, 4.31 for triclosan, 3.89 for chlorhexidine, and 3.17 for reference soap). Professionals remarked the pleasant aroma and non-dryness of skin when using soap containing TTO.

Keywords: Anti-infective agents; Chlorhexidine; Hand hygiene; Infection control; Local; Tea tree oil; Triclosan.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / pharmacology
  • Chlorhexidine / chemistry
  • Chlorhexidine / pharmacology*
  • Cross-Over Studies
  • Hand Hygiene*
  • Humans
  • Middle Aged
  • Skin / drug effects
  • Soaps / chemistry
  • Soaps / pharmacology*
  • Tea Tree Oil / chemistry*
  • Tea Tree Oil / pharmacology*
  • Triclosan / chemistry
  • Triclosan / pharmacology*
  • Young Adult

Substances

  • Anti-Infective Agents
  • Soaps
  • Triclosan
  • Tea Tree Oil
  • Chlorhexidine