Successful Sodium Level Correction with a 3% Saline Bolus before Intermittent Hemodialysis for a Patient with Severe Hyponatremia Accompanied by Acute Kidney Injury

Intern Med. 2021 Aug 15;60(16):2645-2649. doi: 10.2169/internalmedicine.6667-20. Epub 2021 Mar 1.

Abstract

A 60-year-old man presented to the emergency department with lightheadedness. He had severe hyponatremia (109 mEq/L) complicated by acute kidney injury (AKI) (serum creatinine: 9.08 mg/dL). Because he was somnolescent, his hyponatremia was initially treated by administering a 130-mL bolus of 3% saline 2 to 5 times per day for 5 days. He subsequently underwent intermittent hemodialysis without any neurological problems. Previous reports have described patients with hyponatremia and AKI being treated with continuous renal replacement therapy. However, our strategy might be a feasible, low-cost treatment strategy of treating patients with hyponatremia and AKI who do not require immediate hemodialysis.

Keywords: 3% saline bolus administration; acute kidney injury; hemodialysis; hyponatremia; osmotic demyelination syndrome.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury* / complications
  • Acute Kidney Injury* / therapy
  • Humans
  • Hyponatremia* / complications
  • Hyponatremia* / therapy
  • Male
  • Middle Aged
  • Renal Dialysis
  • Saline Solution
  • Sodium

Substances

  • Saline Solution
  • Sodium