Prospective Study of Surgery for Traumatic Brain Injury in Addis Ababa, Ethiopia: Surgical Procedures, Complications, and Postoperative Outcomes

World Neurosurg. 2021 Jun:150:e316-e323. doi: 10.1016/j.wneu.2021.03.004. Epub 2021 Mar 8.

Abstract

Background: Traumatic brain injury (TBI) is an important cause of trauma-related mortality and morbidity in Ethiopia. There are significant resource limitations along the entire continuum of care, and little is known about the neurosurgical activity and patient outcomes.

Methods: All surgically treated TBI patients at the 4 teaching hospitals in Addis Ababa, Ethiopia were prospectively registered from October 2012 to December 2016. Data registration included surgical procedures, complications, reoperations, discharge outcomes, and mortality.

Results: A total of 1087 patients were included. The most common procedures were elevation of depressed skull fractures (49.5%) and craniotomies (47.9%). Epidural hematoma was the most frequent indication for a craniotomy (74.7%). Most (77.7%) patients were operated within 24 hours of admission. The median hospital stay for depressed skull fracture operations or craniotomies was 4 days. Decompressive craniectomy was only done in 10 patients. Postoperative complications were seen in 17% of patients, and only 3% were reoperated. Cerebrospinal fluid leak was the most common complication (7.9%). The overall mortality was 8.2%. Diagnosis, admission Glasgow Coma Scale (GCS) score, surgical procedure, and complications were significant predictors of discharge GCS score (P < 0.01). Age, admission GCS score, and length of hospital stay were significantly associated with mortality (P ≤ 0.005).

Conclusions: The injury panorama, surgical activity, and outcome are significantly influenced by patient selection due to deficits within both prehospital and hospital care. Still, the neurosurgical services benefit a large number of patients in the greater Addis region and are qualitatively comparable with reports from high-income countries.

Keywords: Low- and middle-income countries; Neurotrauma; Surgical outcome; Traumatic brain injury.

MeSH terms

  • Adolescent
  • Adult
  • Brain Injuries, Traumatic / complications*
  • Brain Injuries, Traumatic / mortality
  • Brain Injuries, Traumatic / surgery*
  • Cerebrospinal Fluid Leak / epidemiology
  • Cohort Studies
  • Craniotomy / statistics & numerical data
  • Decompressive Craniectomy / statistics & numerical data
  • Emergency Medical Services / statistics & numerical data
  • Ethiopia
  • Female
  • Glasgow Coma Scale
  • Humans
  • Length of Stay
  • Male
  • Middle Aged
  • Neurosurgical Procedures / statistics & numerical data*
  • Postoperative Complications / epidemiology
  • Prospective Studies
  • Reoperation / statistics & numerical data
  • Skull Fractures / surgery
  • Time-to-Treatment
  • Treatment Outcome
  • Young Adult