Coding-Complete Genome Sequences and Mutation Profiles of Nine SARS-CoV-2 Strains Detected from COVID-19 Patients in Bangladesh

Nihad Adnan; Mohib Ullah Khondoker; M Shaminur Rahman; M Firoz Ahmed; Shahana Sharmin; Nadim Sharif; Nafisa Azmuda; Salma Akter; Shamsun Nahar; Taslin Jahan Mou; Mahfuza Marzan; Syeda Moriam Liza; Nowshin Jahan; Tamanna Ali; Shahad Saif Khandker; Maha Jamiruddin; Mousumi Akter Chaity; Laura Grace Caller; M Ahsanul Haq; Mohd Raeed Jamiruddin

doi:10.1128/MRA.00124-21

Coding-Complete Genome Sequences and Mutation Profiles of Nine SARS-CoV-2 Strains Detected from COVID-19 Patients in Bangladesh

Microbiol Resour Announc. 2021 Mar 11;10(10):e00124-21. doi: 10.1128/MRA.00124-21.

Authors

Nihad Adnan^{1

2}, Mohib Ullah Khondoker^{2

3

4}, M Shaminur Rahman⁵, M Firoz Ahmed¹, Shahana Sharmin⁶, Nadim Sharif¹, Nafisa Azmuda¹, Salma Akter¹, Shamsun Nahar¹, Taslin Jahan Mou¹, Mahfuza Marzan¹, Syeda Moriam Liza¹, Nowshin Jahan², Tamanna Ali², Shahad Saif Khandker², Maha Jamiruddin², Mousumi Akter Chaity², Laura Grace Caller⁷, M Ahsanul Haq², Mohd Raeed Jamiruddin^{8

6}

Affiliations

¹ Department of Microbiology, Jahangirnagar University, Savar, Dhaka, Bangladesh.
² Gonoshasthaya-RNA Molecular Diagnostic and Research Center, Dhanmondi, Dhaka, Bangladesh.
³ Gonoshasthaya Samaj Vittik Medical College, Savar, Dhaka, Bangladesh.
⁴ Center for Multidisciplinary Research, Gono Bishwabidyalay, Savar, Dhaka, Bangladesh.
⁵ Department of Microbiology, University of Dhaka, Dhaka, Bangladesh.
⁶ Department of Pharmacy, BRAC University, Dhaka, Bangladesh.
⁷ Department of Pathology, University of Cambridge, Cambridge, United Kingdom.
⁸ Gonoshasthaya-RNA Molecular Diagnostic and Research Center, Dhanmondi, Dhaka, Bangladesh [email protected].

Abstract

Here, we report the coding-complete genome sequences of nine clinical severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and their mutations. The samples were collected from nine Bangladeshi coronavirus disease 2019 (COVID-19) patients. We have identified the E484K escape mutation and the S359T mutation within the spike protein coding region of the sequenced genomes.