Tenofovir, pregnancy and renal function changes in pregnant women living with HIV

AIDS. 2021 Jul 1;35(8):1319-1320. doi: 10.1097/QAD.0000000000002880.

Abstract

This retrospective study of 100 pregnant women living with HIV [66 on tenofovir disoproxil fumarate (TDF) compared to 34 women on tenofovir alafenamide (TAF)] found no significant difference in renal function in pregnant women with HIV receiving TDF versus TAF. Our results demonstrate that, in regard to renal toxicity, both TDF and TAF appear to be safe for pregnant women living with HIV, but larger prospective cohort studies in pregnant women living with HIV are encouraged.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Anti-HIV Agents* / adverse effects
  • Female
  • HIV Infections* / complications
  • HIV Infections* / drug therapy
  • Humans
  • Pregnancy
  • Pregnant People
  • Prospective Studies
  • Retrospective Studies
  • Tenofovir / adverse effects

Substances

  • Anti-HIV Agents
  • Tenofovir