Abstract
Prospective serosurveillance of severe acute respiratory syndrome coronavirus 2 in 1,069 healthcare workers in London, UK, demonstrated that nucleocapsid antibody titers were stable and sustained for <12 weeks in 312 seropositive participants. This finding was consistent across demographic and clinical variables and contrasts with reports of short-term antibody waning.
Keywords:
COVID-19; London; SARS-CoV-2; antibodies; coronavirus disease; epidemiology; health personnel; healthcare workers; respiratory infections; serology; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Antibodies, Viral / blood*
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Antibody Formation / immunology*
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COVID-19 Serological Testing* / methods
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COVID-19 Serological Testing* / statistics & numerical data
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COVID-19* / diagnosis
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COVID-19* / epidemiology
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COVID-19* / immunology
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Coronavirus Nucleocapsid Proteins / immunology*
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Female
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Health Personnel / statistics & numerical data*
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Humans
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London / epidemiology
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Male
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Phosphoproteins / immunology
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SARS-CoV-2 / isolation & purification
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Seroconversion
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Seroepidemiologic Studies
Substances
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Antibodies, Viral
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Coronavirus Nucleocapsid Proteins
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Phosphoproteins
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nucleocapsid phosphoprotein, SARS-CoV-2