Sharing a household with children and risk of COVID-19: a study of over 300 000 adults living in healthcare worker households in Scotland

Arch Dis Child. 2021 Dec;106(12):1212-1217. doi: 10.1136/archdischild-2021-321604. Epub 2021 Mar 18.

Abstract

Objective: Children are relatively protected from COVID-19, due to a range of potential mechanisms. We investigated if contact with children also affords adults a degree of protection from COVID-19.

Design: Cohort study based on linked administrative data.

Setting: Scotland.

Study population: All National Health Service Scotland healthcare workers and their household contacts as of March 2020.

Main exposure: Number of young children (0-11 years) living in the participant's household.

Main outcomes: COVID-19 requiring hospitalisation, and any COVID-19 (any positive test for SARS-CoV-2) in adults aged ≥18 years between 1 March and 12 October 2020.

Results: 241 266, 41 198, 23 783 and 3850 adults shared a household with 0, 1, 2 and 3 or more young children, respectively. Over the study period, the risk of COVID-19 requiring hospitalisation was reduced progressively with increasing numbers of household children-fully adjusted HR (aHR) 0.93 per child (95% CI 0.79 to 1.10). The risk of any COVID-19 was similarly reduced, with the association being statistically significant (aHR per child 0.93; 95% CI 0.88 to 0.98). After schools reopened to all children in August 2020, no association was seen between exposure to young children and risk of any COVID-19 (aHR per child 1.03; 95% CI 0.92 to 1.14).

Conclusion: Between March and October 2020, living with young children was associated with an attenuated risk of any COVID-19 and COVID-19 requiring hospitalisation among adults living in healthcare worker households. There was no evidence that living with young children increased adults' risk of COVID-19, including during the period after schools reopened.

Keywords: COVID-19; epidemiology.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • COVID-19 / diagnosis
  • COVID-19 / immunology
  • COVID-19 / transmission*
  • COVID-19 Testing
  • Child
  • Child, Preschool
  • Cohort Studies
  • Cross Protection
  • Family Characteristics*
  • Female
  • Health Personnel*
  • Hospitalization
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Pandemics
  • Risk Factors
  • SARS-CoV-2
  • Schools
  • Scotland / epidemiology