Day at the Races: Comparing BioFire FilmArray Blood Culture ID Panels With Verigene Blood Culture Panel in Gram-Negative Bloodstream Infections Using DOOR-MAT Analysis

Kimberly C Claeys; Kathryn Schlaffer; Richard Smith; Stephanie Hitchcock; Yunyun Jiang; Scott Evans; J Kristie Johnson; Surbhi Leekha

doi:10.1093/cid/ciab262

Day at the Races: Comparing BioFire FilmArray Blood Culture ID Panels With Verigene Blood Culture Panel in Gram-Negative Bloodstream Infections Using DOOR-MAT Analysis

Clin Infect Dis. 2021 Sep 15;73(6):1103-1106. doi: 10.1093/cid/ciab262.

Authors

Kimberly C Claeys¹, Kathryn Schlaffer², Richard Smith³, Stephanie Hitchcock³, Yunyun Jiang⁴, Scott Evans⁴, J Kristie Johnson³, Surbhi Leekha⁵

Affiliations

¹ Department of Pharmacy Practice and Science, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
² Department of Medicine, University of Maryland Medical Center, Baltimore, Maryland, USA.
³ Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
⁴ Biostatistics Center and the Department of Biostatistics and Bioinformatics, The George Washington University, Washington D.C., USA.
⁵ Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Abstract

Three rapid diagnostic test panels (Verigene BC-GN, BioFire BCID, and BCID 2 [RUO]) were compared using the Desirability of Outcome Ranking Management of Antimicrobial Therapy (DOOR-MAT) to evaluate potential downstream antimicrobial prescribing decisions resulting from the panels' different organism and resistance detection. BioFire BCID 2 (RUO) had the best mean DOOR-MAT scores.

Keywords: bloodstream infections; gram-negative; rapid diagnostic testing.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Anti-Infective Agents*
Bacteremia* / diagnosis
Blood Culture
Humans
Molecular Diagnostic Techniques
Sepsis*

Substances

Anti-Infective Agents

Grants and funding

BioFire Diagnostics