Recurrent Mixed Neuroendocrine-Non-Neuroendocrine Neoplasm in the Gallbladder: A Case Report

Turki Al-Fayea; Mohammed Alzahrani; Hatim Almaghrabi; Abdulrahman Alghamdi; Kabo Mohammed

doi:10.1159/000513031

Recurrent Mixed Neuroendocrine-Non-Neuroendocrine Neoplasm in the Gallbladder: A Case Report

Case Rep Oncol. 2021 Mar 11;14(1):411-417. doi: 10.1159/000513031. eCollection 2021 Jan-Apr.

Authors

Turki Al-Fayea^{1

2

3}, Mohammed Alzahrani^{1

2

4}, Hatim Almaghrabi^{1

2

5}, Abdulrahman Alghamdi^{1

2}, Kabo Mohammed^{1

2

3}

Affiliations

¹ College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
² King Abdullah International Medical Research Center, Jeddah, Saudi Arabia.
³ Department of Medical Oncology, Princess Noorah Oncology Center, King Abdulaziz Medical City, Jeddah, Saudi Arabia.
⁴ Department of Surgery, King Abdulaziz Medical City, Jeddah, Saudi Arabia.
⁵ Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City, Jeddah, Saudi Arabia.

Abstract

Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) of the gallbladder are rare with no established therapeutic strategies. We report a case of recurrent gallbladder MiNEN from a population with a low incidence of gallbladder carcinomas, a review of the current therapeutic options, and recent updates on the nomenclature proposed by the World Health Organization in 2017.

Keywords: Gallbladder neoplasms; Mixed neuroendocrine-non-neuroendocrine neoplasm; Neuroendocrine tumors.

Publication types

Case Reports