The influence of chronic N-methyl-N'-nitro-N-nitrosoguanidine pre-treatments on mutagenic response and O6-methylguanine-DNA methyltransferase activity in V79 Chinese hamster cells

Mutat Res. 1988 Jun;208(2):73-6. doi: 10.1016/s0165-7992(98)90002-1.
No abstract available

MeSH terms

  • Animals
  • Cricetinae
  • Cricetulus
  • DNA Damage*
  • DNA Repair / drug effects*
  • Drug Resistance
  • Fibroblasts / drug effects
  • Fibroblasts / metabolism
  • Lung
  • Male
  • Methylnitronitrosoguanidine / pharmacology*
  • Methylnitrosourea / pharmacology
  • Methyltransferases / metabolism*
  • Mutation
  • O(6)-Methylguanine-DNA Methyltransferase

Substances

  • Methylnitronitrosoguanidine
  • Methylnitrosourea
  • Methyltransferases
  • O(6)-Methylguanine-DNA Methyltransferase