Harnessing the Metabolic Vulnerabilities of Leukemia Stem Cells to Eradicate Acute Myeloid Leukemia

Front Oncol. 2021 Mar 17:11:632789. doi: 10.3389/fonc.2021.632789. eCollection 2021.

¹ Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX, United States.

No abstract available

Keywords: DHODH inhibitor; NAMPT; bone marrow niche; drug resistance; leukemia stem cells; metabolism; oxidative phosphorylation.