Mortality and Morbidities according to Time of Birth in Extremely Low Birth Weight Infants

J Korean Med Sci. 2021 Apr 5;36(13):e86. doi: 10.3346/jkms.2021.36.e86.

Abstract

Background: Although the overall quality of high-risk neonatal care has improved recently, there is still concern about a difference in the quality of care when comparing off-hour births and regular-hour births. Moreover, there are no data in Korea regarding the impact of time of birth on mortality and morbidities in preterm infants.

Methods: A total of 3,220 infants weighing < 1,000 g and born at 23-34 weeks in 2013-2017 were analyzed based on the Korean Neonatal Network data. Mortality and major morbidities were analyzed using logistic regression according to time of birth during off-hours (nighttime, weekend, and holiday) and regular hours. The institutes were sub-grouped into hospital group I and hospital group II based on the neonatal intensive care unit (NICU) care level defined by the mortality rates of < 50% and ≥ 50%, respectively, in infants born at 23-24 weeks' gestation.

Results: The number of births during regular hours and off-hours was similar. In the total population and hospital group I, off-hour births were not associated with increased neonatal mortality and morbidities. However, in hospital group II, increased early mortality was found in the off-hour births when compared to regular-hour births.

Conclusion: Efforts to improve the overall quality of NICU are required to lower the early mortality rate in off-hour births. Also, other sensitive indexes for the evaluation of quality of NICU care should be further studied.

Keywords: After-hours Care; Neonatal Intensive Care; Neonatal Mortality; Preterm Infants; Quality of Health Care.

MeSH terms

  • After-Hours Care
  • Cerebral Intraventricular Hemorrhage / epidemiology
  • Cerebral Intraventricular Hemorrhage / mortality
  • Databases, Factual
  • Enterocolitis, Necrotizing / epidemiology
  • Enterocolitis, Necrotizing / mortality
  • Female
  • Gestational Age
  • Humans
  • Infant
  • Infant Mortality
  • Infant, Extremely Low Birth Weight
  • Infant, Newborn
  • Infant, Premature, Diseases / epidemiology*
  • Infant, Premature, Diseases / mortality
  • Intensive Care Units, Neonatal
  • Logistic Models
  • Male
  • Morbidity
  • Odds Ratio
  • Quality of Health Care
  • Republic of Korea
  • Time Factors