New scavenger to fine-tune insulin action in β cells

Catherine Hall; Eunhee Choi

doi:10.1016/j.cmet.2021.03.013

New scavenger to fine-tune insulin action in β cells

Cell Metab. 2021 Apr 6;33(4):707-708. doi: 10.1016/j.cmet.2021.03.013.

Authors

Catherine Hall¹, Eunhee Choi²

Affiliations

¹ Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168(th) Street, New York, NY 10032, USA.
² Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168(th) Street, New York, NY 10032, USA. Electronic address: [email protected].

PMID: 33826914
DOI: 10.1016/j.cmet.2021.03.013

Abstract

Insulin receptor signaling is crucial for β cell homeostasis. In a recent issue of Nature, Ansarullah et al. (2021) have identified the insulin inhibitory receptor (inceptor), which balances insulin signaling by promoting insulin receptor internalization.

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MeSH terms

Homeostasis
Insulin
Insulin-Secreting Cells*
Signal Transduction

Substances

Insulin