Background: The National Institutes of Health Science of Behavior Change Common Fund Program has accelerated the investigation of mechanisms of behavior change applicable to multiple health behaviors and outcomes and facilitated the use of the experimental medicine approach to behavior change research.
Purpose: This commentary provides a brief background of the program, plans for its next phase, and thoughts about how the experimental medicine approach to behavior change research can inform future directions in two areas of science-reproductive health and COVID-19 vaccine uptake.
Conclusions: The incorporation of a mechanisms-based approach into behavior intervention research offers new opportunities for improving health.
Keywords: COVID-19 vaccine uptake; Experimental medicine approach; Mechanisms of behavior change; NIH; Reproductive health; Science of behavior change.
Published by Oxford University Press on behalf of the Society of Behavioral Medicine 2021.