Vascular Regenerative Capacity and the Obesity Paradox in Coronary Artery Disease

Arterioscler Thromb Vasc Biol. 2021 Jun;41(6):2097-2108. doi: 10.1161/ATVBAHA.120.315703. Epub 2021 Apr 15.

Abstract

[Figure: see text].

Keywords: body mass index; cardiovascular diseases; inflammation; stem cells.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • AC133 Antigen / blood
  • Adult
  • Antigens, CD34 / blood
  • Biomarkers / blood
  • Cell Count
  • Coronary Artery Disease / blood
  • Coronary Artery Disease / mortality
  • Coronary Artery Disease / pathology*
  • Coronary Artery Disease / physiopathology
  • Female
  • Humans
  • Incidence
  • Leukocyte Common Antigens / blood
  • Male
  • Middle Aged
  • Obesity / blood
  • Obesity / mortality
  • Obesity / pathology*
  • Obesity / physiopathology
  • Phenotype
  • Prognosis
  • Receptors, CXCR4 / blood
  • Regeneration*
  • Registries
  • Risk Assessment
  • Risk Factors
  • Stem Cells / metabolism
  • Stem Cells / pathology*
  • Time Factors
  • Vascular Remodeling*

Substances

  • AC133 Antigen
  • Antigens, CD34
  • Biomarkers
  • CXCR4 protein, human
  • PROM1 protein, human
  • Receptors, CXCR4
  • Leukocyte Common Antigens
  • PTPRC protein, human