The future of genomics in Ireland - focus on genomics for health

HRB Open Res. 2020 Dec 4:3:89. doi: 10.12688/hrbopenres.13187.1. eCollection 2020.

Abstract

Genomics is revolutionizing biomedical research, medicine and healthcare globally in academic, public and industry sectors alike. Concrete examples around the world show that huge benefits for patients, society and economy can be accrued through effective and responsible genomic research and clinical applications. Unfortunately, Ireland has fallen behind and needs to act now in order to catch up. Here, we identify key issues that have resulted in Ireland lagging behind, describe how genomics can benefit Ireland and its people and outline the measures needed to make genomics work for Ireland and Irish patients. There is now an urgent need for a national genomics strategy that enables an effective, collaborative, responsible, well-regulated, and patient centred environment where genome research and clinical genomics can thrive. We present eight recommendations that could be the pillars of a national genomics health strategy.

Keywords: Genomics; ethics of genome research; genome research; health-economic assessment of clinical genomics; national genomics strategy; patient involvement; precision/personalized medicine; societal and economic aspects of genome research.

Grants and funding

Health Research Board Ireland [DIFA-2018-028, COV19-2020-123, CRCI-OR-2020-6 UCD to PD; HRB-ILP-POR-2017-078 to APB]. The authors also acknowledge funding from the Science Foundation Ireland [18/SPP/3522 and 14/IA/2395 to WK; 16/IA/4612 and 18/CRT/6214 to CS].