ORACLE reveals a bright future to fight bacteria

Elife. 2021 Apr 15:10:e68277. doi: 10.7554/eLife.68277.

Abstract

A new way to alter the genome of bacteriophages helps produce large libraries of variants, allowing these bacteria-killing viruses to be designed to target species harmful to human health.

Keywords: bacteriophage; biochemistry; chemical biology; deep mutational scanning; phage; synthetic biology; tail fiber; virus; virus engineering.

Publication types

  • Comment

MeSH terms

  • Bacteria / genetics
  • Bacteriophages* / genetics
  • Humans