Invasive ACTH-producing pituitary gland neoplasm secondary to MSH2 mutation

P B Loughrey; G Baker; B Herron; S Cooke; D Iacovazzo; J R Lindsay; M Korbonits

doi:10.1016/j.cancergen.2021.03.008

Invasive ACTH-producing pituitary gland neoplasm secondary to MSH2 mutation

Cancer Genet. 2021 Aug:256-257:36-39. doi: 10.1016/j.cancergen.2021.03.008. Epub 2021 Apr 4.

Authors

P B Loughrey¹, G Baker², B Herron², S Cooke³, D Iacovazzo⁴, J R Lindsay⁵, M Korbonits⁶

Affiliations

¹ Regional Center for Endocrinology and Diabetes, Royal Victoria Hospital, Belfast Health and Social Care Trust, UK; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, UK.
² Cellular Pathology, Royal Victoria Hospital, Belfast Health and Social Care Trust, UK.
³ Department of Neurosurgery, Royal Victoria Hospital, Belfast Health and Social Care Trust, UK.
⁴ Centre for Endocrinology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
⁵ Regional Center for Endocrinology and Diabetes, Royal Victoria Hospital, Belfast Health and Social Care Trust, UK; Mater Infirmorum Hospital, Belfast Health and Social Care Trust, UK.
⁶ Centre for Endocrinology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. Electronic address: [email protected].

PMID: 33866195
DOI: 10.1016/j.cancergen.2021.03.008

No abstract available

Keywords: ACTH-Secreting pituitary adenoma (D049913); ACTH-producing pituitary gland neoplasm (C7909); Cancer Ontology Keywords; Corticotroph Adenoma (C7462); Disease ontology – ACTH-secreting pituitary adenoma (7004); Hereditary (D009386); MeSH – ACTH-secreting pituitary adenoma (D049913); Muts homolog 2 protein (D051718), Lynch syndrome II (D055847); NCI Thesaurus – ACTH-producing pituitary gland neoplasm (C7909); Neoplastic syndromes; Neuroendocrine tumors (D018358); Oncotree – pituitary adenoma.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adrenocorticotropic Hormone / biosynthesis*
Adult
Base Sequence
Dexamethasone / therapeutic use
Dose-Response Relationship, Drug
Female
Heterozygote
Humans
Magnetic Resonance Imaging
MutS Homolog 2 Protein / genetics*
Mutation / genetics*
Neoplasm Invasiveness
Pituitary Neoplasms / diagnostic imaging
Pituitary Neoplasms / drug therapy
Pituitary Neoplasms / genetics*
Tomography, X-Ray Computed

Substances

Dexamethasone
Adrenocorticotropic Hormone
MSH2 protein, human
MutS Homolog 2 Protein

Grants and funding

MR/M018539/1/MRC_/Medical Research Council/United Kingdom