Abstract
Two adults with malignant optic gliomas displayed dramatic tumor shrinkage and prolonged survival after radiation therapy alone in one case and combined radiation and chemotherapy in the other. Although malignant optic gliomas have been reported to be radiation resistant, marked treatment response may occur and aggressive treatment protocols should be considered.
Publication types
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Case Reports
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Adult
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Bromodeoxyuridine / therapeutic use
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Cranial Nerve Neoplasms / drug therapy
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Cranial Nerve Neoplasms / pathology
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Cranial Nerve Neoplasms / radiotherapy*
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Female
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Follow-Up Studies
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Glioma / drug therapy
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Glioma / pathology
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Glioma / radiotherapy*
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Humans
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Lomustine / administration & dosage
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Male
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Middle Aged
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Neoplasm Invasiveness
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Optic Nerve Diseases / drug therapy
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Optic Nerve Diseases / pathology
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Optic Nerve Diseases / radiotherapy*
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Procarbazine / administration & dosage
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Vincristine / administration & dosage
Substances
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Procarbazine
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Vincristine
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Lomustine
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Bromodeoxyuridine