Engrafted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Undergo Clonal Expansion In Vivo

Danny El-Nachef; Darrian Bugg; Kevin M Beussman; Sonette Steczina; Amy M Martinson; Charles E Murry; Nathan J Sniadecki; Jennifer Davis

doi:10.1161/CIRCULATIONAHA.119.044974

Engrafted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Undergo Clonal Expansion In Vivo

Circulation. 2021 Apr 20;143(16):1635-1638. doi: 10.1161/CIRCULATIONAHA.119.044974. Epub 2021 Apr 19.

Authors

Danny El-Nachef^{1

2

3}, Darrian Bugg^{1

2

3}, Kevin M Beussman^{2

4

3}, Sonette Steczina^{2

5

3}, Amy M Martinson^{1

2

3}, Charles E Murry^{1

2

5

3}, Nathan J Sniadecki^{1

2

5

4

3}, Jennifer Davis^{1

2

5

3}

Affiliations

¹ Department of Laboratory Medicine and Pathology (D.E.-N., D.B., A.M.M., C.E.M., N.J.S., J.D.), University of Washington, Seattle.
² Institute for Stem Cell and Regenerative Medicine (D.E.-N., D.B., K.M.B., S.S., A.M.M., C.E.M., N.J.S., J.D.), University of Washington, Seattle.
³ Center for Cardiovascular Biology (D.E.-N., D.B., K.M.B., S.S., A.M.M., C.E.M., N.J.S., J.D.), University of Washington, Seattle.
⁴ Department of Mechanical Engineering (K.M.B., N.J.S.), University of Washington, Seattle.
⁵ Department of Bioengineering (S.S., C.E.M., N.J.S., J.D.), University of Washington, Seattle.

No abstract available

Keywords: cellular proliferation; heart; hypertrophy; myocyte; regeneration.

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Cell Differentiation
Humans
Induced Pluripotent Stem Cells / transplantation*
Myocytes, Cardiac / transplantation*

Publication types

MeSH terms

Grants and funding