Genomic and pathogenicity of a Bacillus paranthracis isolated from book page surface

Infect Genet Evol. 2021 Aug:92:104867. doi: 10.1016/j.meegid.2021.104867. Epub 2021 Apr 16.

Abstract

I report here the genome sequences of a Bacillus paranthracis strain isolated from book page surface. The presented data show a new study field for this species, which is frequently encountered in several environment, including soil, rhizosphere and notably human samples. I provide some insights about genomic content of Bacillus paranthracis, for example the presence of multiple antibiotic resistance genes, genes for polyhydroxybutyrate metabolism, 120 genes related to stress resistance and pathogenicity-related genes such as phospholipase C, metalloprotease and a cluster for non-hemolytic enterotoxin. In vitro tests showed that this isolate has motility, ability to produce biofilm, cytotoxic and enterotoxic ability, which makes this isolate a potential pathogen.

Keywords: Bacillus paranthracis; Book surface; Complete genome; Pathogenesis.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacillus / genetics*
  • Bacillus / isolation & purification
  • Bacillus / pathogenicity*
  • Books*
  • Brazil
  • Drug Resistance, Bacterial / genetics*
  • Genome, Bacterial*
  • Virulence

Substances

  • Anti-Bacterial Agents

Supplementary concepts

  • Bacillus paranthracis