[Assessment and intervention strategies for sarcopenia in patients with liver cirrhosis]

Zhonghua Gan Zang Bing Za Zhi. 2021 Mar 20;29(3):199-203. doi: 10.3760/cma.j.cn501113-20210113-00025.
[Article in Chinese]

Abstract

Sarcopenia is a common complication in patients with liver cirrhosis, which has an adverse effect on the clinical outcome and prognosis. Attention must be paid to early detection and active diagnosis and treatment. Clinically, the diagnosis process of finding suspicious cases can be traced through screening-assessment-diagnosis-severity evaluation. On the ground of treating liver cirrhosis and its complications, reasonable nutritional intervention and exercise are currently important measures for the treatment of liver cirrhosis with sarcopenia, and the role of hormone supplementation and drug therapy for skeletal muscle metabolism needs to be further investigated.

肌肉减少症是肝硬化患者常见的并发症,对患者的临床结局和预后具有不良影响,需要予以足够重视,及早发现,积极诊治。临床上,可遵循发现可疑病例(筛查)—评估—确诊—严重程度评估的诊断流程。针对肝硬化及其并发症治疗基础上,合理的营养干预和运动是目前肝硬化合并肌少症治疗的重要措施,激素补充、针对骨骼肌代谢途径药物治疗的作用尚需要进一步证实。.

Keywords: Assessment; Liver cirrhosis; Sarcopenia; Strategy; Treatment.

MeSH terms

  • Humans
  • Liver Cirrhosis / complications
  • Liver Cirrhosis / pathology
  • Muscle, Skeletal / pathology
  • Prognosis
  • Sarcopenia* / diagnosis
  • Sarcopenia* / etiology
  • Sarcopenia* / therapy