Multimodality Imaging Review of Multiple Endocrine Neoplasia

AJR Am J Roentgenol. 2021 Jul;217(1):245-256. doi: 10.2214/AJR.20.22933. Epub 2021 Apr 28.

Abstract

OBJECTIVE. The purpose of this article is to review the clinical manifestations, endocrine tumors types, and multimodality diagnostic tools available to physicians involved in the management of patients with multiple endocrine neoplasia (MEN) syndrome, in addition to discussing relevant imaging findings and appropriate imaging follow-up. CONCLUSION. Thorough knowledge of the spectrum of tumors associated with MEN gene mutations aids in the screening, diagnostic workup, and posttreatment monitoring of patients with MEN-related gene mutations.

Keywords: medullary thyroid carcinoma; multiple endocrine neoplasia; pancreatic neuroendocrine tumor; parathyroid adenoma; pheochromocytoma; pituitary adenoma.

Publication types

  • Review

MeSH terms

  • Endocrine Glands / diagnostic imaging
  • Humans
  • Multimodal Imaging / methods*
  • Multiple Endocrine Neoplasia / diagnostic imaging*
  • Tomography Scanners, X-Ray Computed
  • Tomography, Emission-Computed, Single-Photon
  • Ultrasonography