Role of Functional Magnetic Resonance Imaging in the Presurgical Mapping of Brain Tumors

Rozita Jalilianhasanpour; Elham Beheshtian; Daniel Ryan; Licia P Luna; Shruti Agarwal; Jay J Pillai; Haris I Sair; Sachin K Gujar

doi:10.1016/j.rcl.2021.02.001

Role of Functional Magnetic Resonance Imaging in the Presurgical Mapping of Brain Tumors

Radiol Clin North Am. 2021 May;59(3):377-393. doi: 10.1016/j.rcl.2021.02.001.

Authors

Rozita Jalilianhasanpour¹, Elham Beheshtian¹, Daniel Ryan¹, Licia P Luna¹, Shruti Agarwal¹, Jay J Pillai², Haris I Sair³, Sachin K Gujar⁴

Affiliations

¹ Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
² Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA; Department of Neurosurgery, Johns Hopkins University School of Medicine, 1800 Orleans Street, Baltimore, MD 21287, USA.
³ Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA; The Malone Center for Engineering in Healthcare, The Whiting School of Engineering, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA.
⁴ Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA. Electronic address: [email protected].

PMID: 33926684
DOI: 10.1016/j.rcl.2021.02.001

Abstract

When planning for brain tumor resection, a balance between maximizing resection and minimizing injury to eloquent brain parenchyma is paramount. The advent of blood oxygenation level-dependent functional magnetic resonance (fMR) imaging has allowed researchers and clinicians to reliably measure physiologic fluctuations in brain oxygenation related to neuronal activity with good spatial resolution. fMR imaging can offer a unique insight into preoperative planning for brain tumors by identifying eloquent areas of the brain affected or spared by the neoplasm. This article discusses the fMR imaging techniques and their applications in neurosurgical planning.

Keywords: Brain mapping; Functional MR imaging; Presurgical mapping; Resting state fMR imaging; Task fMR imaging.

Publication types

Review

MeSH terms

Brain / diagnostic imaging
Brain / surgery
Brain Mapping / methods*
Brain Neoplasms / diagnostic imaging*
Brain Neoplasms / surgery
Humans
Magnetic Resonance Imaging / methods*
Preoperative Care / methods*