Frailty and length of stay in older adults with blunt injury in a national multicentre prospective cohort study

PLoS One. 2021 Apr 30;16(4):e0250803. doi: 10.1371/journal.pone.0250803. eCollection 2021.

Abstract

Background: Patients suffering moderate or severe injury after low falls have higher readmission and long-term mortality rates compared to patients injured by high-velocity mechanisms such as motor vehicle accidents. We hypothesize that this is due to higher pre-injury frailty in low-fall patients, and present baseline patient and frailty demographics of a prospective cohort of moderate and severely injured older patients. Our second hypothesis was that frailty was associated with longer length of stay (LOS) at index admission.

Methods: This is a prospective, nation-wide, multi-center cohort study of Singaporean residents aged ≥55 years admitted for ≥48 hours after blunt injury with an injury severity score or new injury severity score ≥10, or an Organ Injury Scale ≥3, in public hospitals from 2016-2018. Demographics, mechanism of injury and frailty were recorded and analysed by Chi-square, or Kruskal-Wallis as appropriate.

Results: 218 participants met criteria and survived the index admission. Low fall patients had the highest proportion of frailty (44, 27.3%), followed by higher level fallers (3, 21.4%) and motor vehicle accidents (1, 2.3%) (p < .01). Injury severity, extreme age, and surgery were independently associated with longer LOS. Frail patients were paradoxically noted to have shorter LOS (p < .05).

Conclusion: Patients sustaining moderate or severe injury after low falls are more likely to be frail compared to patients injured after higher-velocity mechanisms. However, this did not translate into longer adjusted LOS in hospital at index admission.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Accidental Falls / statistics & numerical data
  • Accidents, Traffic
  • Aged
  • Female
  • Frail Elderly / statistics & numerical data*
  • Frailty
  • Geriatric Assessment
  • Hospitalization / statistics & numerical data*
  • Humans
  • Injury Severity Score
  • Length of Stay / statistics & numerical data*
  • Male
  • Middle Aged
  • Prospective Studies
  • Singapore / epidemiology
  • Wounds, Nonpenetrating / epidemiology
  • Wounds, Nonpenetrating / therapy*

Grants and funding

This work was supported by the National Medical Research Council Health NMRC HSRG (NMRC/HSRG/0054/2016), the Duke-NUS Khoo Pilot Award 2015, and the 2016 SingHealth Medical Student Talent Development Awards – Project, Singapore. One or more of the authors are employed by SingHealth Services. The funders provided support in the form of salaries for authors TXZT, NVN, ASHA, RM, MEHO, DBM, DCCS, YSN, AC, THW, but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. The specific roles of these authors are articulated in the ‘author contributions’ section.