Rational Combination Therapy to Overcome the Plateau of Drug Efficacy in Inflammatory Bowel Disease

Gastroenterology. 2021 Aug;161(2):394-399. doi: 10.1053/j.gastro.2021.04.068. Epub 2021 May 4.

Authors

Carlos Stalgis¹, Parakkal Deepak², Saurabh Mehandru³, Jean-Frederic Colombel³

Affiliations

¹ Ortelius Insight, LLC, Agoura Hills, California.
² Inflammatory Bowel Diseases Center, Division of Gastroenterology, Washington University in St. Louis School of Medicine, St Louis, Missouri.
³ Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York.

PMID: 33961886
DOI: 10.1053/j.gastro.2021.04.068

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Inflammatory Agents / adverse effects
Anti-Inflammatory Agents / therapeutic use*
Biological Products / adverse effects
Biological Products / therapeutic use*
Clinical Decision-Making
Colitis, Ulcerative / diagnosis
Colitis, Ulcerative / drug therapy*
Colitis, Ulcerative / immunology
Drug Synergism
Drug Therapy, Combination
Humans
Remission Induction
Treatment Outcome
Tumor Necrosis Factor Inhibitors / adverse effects
Tumor Necrosis Factor Inhibitors / therapeutic use*

Substances

Anti-Inflammatory Agents
Biological Products
Tumor Necrosis Factor Inhibitors