TP53 disruption as a risk factor in the era of targeted therapies: A multicenter retrospective study of 525 chronic lymphocytic leukemia cases

Affiliations

• ¹ Biotechnology Research Unit, AO of Cosenza, Cosenza, Italy.
• ² Hematology and Bone Marrow Transplant Unit, Hemato-Oncology Department, Augusta Victoria Hospital, East Jerusalem, Israel.
• ³ Division of Hematology, S. Eugenio Hospital and University of Tor Vergata, Rome, Italy.
• ⁴ Hematology, Department of Translational and Precision Medicine, 'Sapienza' University, Rome, Italy.
• ⁵ Ematologia, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.
• ⁶ Centro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, Italy.
• ⁷ Fondazione Universitaria Policlinico A Gemelli di Roma, Rome, Italy.
• ⁸ Division of Hematology, A.O.U. Città della Salute e della Scienza di Torino, Torino, Italy.
• ⁹ Sourasky Medical Center, Institute of Hematology, and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
• ¹⁰ Division of Haematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
• ¹¹ Hematology and Stem Cell Transplantation Unit, Ospedale A. Businco, Cagliari, Italy.
• ¹² Division of Hematology, Policlinico, Department of Surgery and Medical Specialties, University of Catania, Catania, Italy.
• ¹³ Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy.
• ¹⁴ Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
• ¹⁵ Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy.
• ¹⁶ Division of Hematology, Azienda Ospedaliera SS Arrigo e Biagio e Cesare Arrigo, Alessandria, Italy.
• ¹⁷ Hematology and Cell Therapy Unit, IRCCS-Istituto Tumori 'Giovanni Paolo II', Bari, Italy.
• ¹⁸ Hematology Department, G. Garibaldi Hospital, Catania, Italy.
• ¹⁹ Clinica di Ematologia Ospedali Riuniti, Ancona, Italy.
• ²⁰ Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
• ²¹ Hematology Unit, AO of Cosenza, Cosenza, Italy.
• ²² CNR-IFC, Research Unit of Reggio Calabria, Reggio Calabria, Italy.
• ²³ Section of Hematology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
• ²⁴ UOSD Ematologia ASL Roma 1, Rome, Italy.
• ²⁵ Reparto di Oncoematologia Azienda Ospedaliera Santa Maria di Terni, Terni, Italy.
• ²⁶ Mutagenesis and Cancer Prevention Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
• ²⁷ Molecular Pathology Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
• ²⁸ Department of Hematology, Dubrava University Hospital, Zagreb, Croatia.
• ²⁹ AOU Santa Maria della Misericordia, Udine, Italy.
• ³⁰ Hematology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
• ³¹ Department of Hematology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
• ³² Department of Experimental Medicine, University of Genoa, Genoa, Italy.