Successful Treatment of Acanthamoeba Meningoencephalitis in an Immunocompetent Child

Sevliya Öcal Demir; Gülser Esen Besli; Abdulmelik Bucak; Özden Boral; Begümhan Baysal

doi:10.1093/tropej/fmaa102

Successful Treatment of Acanthamoeba Meningoencephalitis in an Immunocompetent Child

J Trop Pediatr. 2021 May 17;67(2):fmaa102. doi: 10.1093/tropej/fmaa102.

Authors

Sevliya Öcal Demir¹, Gülser Esen Besli², Abdulmelik Bucak³, Özden Boral⁴, Begümhan Baysal⁵

Affiliations

¹ SB Istanbul Medeniyet University Goztepe Prof Dr Suleyman Yalcın City Hospital, Pediatric Department, Division of Pediatric Infectious Diseases, Istanbul, Turkey.
² SB Istanbul Medeniyet University Goztepe Prof Dr Suleyman Yalcın City Hospital, Pediatric Department, Division of Pediatric Emergency, Istanbul, Turkey.
³ SB Istanbul Medeniyet University Goztepe Prof Dr Suleyman Yalcın City Hospital, Pediatric Department, Istanbul, Turkey.
⁴ Istanbul University, Istanbul Medical School, Microbiology and Clinic Microbiology Department, Istanbul, Turkey.
⁵ SB Istanbul Medeniyet University Goztepe Prof Dr Suleyman Yalcın City Hospital, Radiology Department, Istanbul, Turkey.

PMID: 33998656
DOI: 10.1093/tropej/fmaa102

Abstract

Acanthamoeba meningoencephalitis is a very rare entity with high mortality rate. Its diagnosis is usually delated, and the optimal approach for its treatment is uncertain. In presented case, early diagnosis was made with direct examination of cerebral spinal fluid, and immediate initiation of accurate treatment with amphotericin B and fluconazole survived patient.

Keywords: Acanthamoeba; amebic; meningoencephalitis.

MeSH terms

Acanthamoeba*
Amebiasis* / diagnosis
Amebiasis* / drug therapy
Central Nervous System Protozoal Infections* / diagnosis
Central Nervous System Protozoal Infections* / drug therapy
Child
Family
Humans
Meningoencephalitis* / diagnosis
Meningoencephalitis* / drug therapy