Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics

Affiliations

• ¹ Division of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY, USA.
• ² Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
• ³ Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
• ⁴ Institute for Behavioral Science, Feinstein Institutes for Medical Research, Manhasset, NY, USA.
• ⁵ Institute of Mental Health, Singapore, Singapore.
• ⁶ Biogen, Inc, Cambridge, MA, USA.
• ⁷ Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
• ⁸ Center for Medical Genetics & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
• ⁹ Psychiatry Department, SUNY Upstate Medical University, Syracuse, NY, USA.
• ¹⁰ Lothian Birth Cohorts, University of Edinburgh, Edinburgh, Scotland, UK.
• ¹¹ Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, UK.
• ¹² Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
• ¹³ Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children's Hospital, Boston, MA, USA.
• ¹⁴ Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
• ¹⁵ Olin Neuropsychic Research Center, Institute of Living, Hartford Hospital, Hartford, CT, USA.
• ¹⁶ Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
• ¹⁷ Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
• ¹⁸ Department of Genetics and Genomic Science and Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
• ¹⁹ Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.
• ²⁰ NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway.
• ²¹ Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
• ²² Spaulding Rehabilitation Hospital Boston, Charlestown, MA, USA.
• ²³ Dr. Einar Martens Research Group for Biological Psychiatry, Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway.
• ²⁴ Department of Psychology, University of Oslo, Oslo, Norway.
• ²⁵ Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.
• ²⁶ Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway.
• ²⁷ Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
• ²⁸ Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
• ²⁹ Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.
• ³⁰ Department of Medical Genetics, University of Helsinki and University Central Hospital, Helsinki, Finland.
• ³¹ Department of General Practice, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
• ³² Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
• ³³ Folkhälsan Research Center, Helsinki, Finland.
• ³⁴ Department of Psychiatry, Martin Luther University of Halle-Wittenberg, Halle, Germany.
• ³⁵ Mental Illness Research, Education, and Clinical Center (VISN 2), James J. Peters VA Medical Center, Bronx, NY, USA.
• ³⁶ Department of Psychology, University of Crete, Crete, Greece.
• ³⁷ Department of Psychiatry - Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
• ³⁸ Division of Informatics, Imaging & Data Sciences, School of Health Sciences, The University of Manchester, Manchester, UK.
• ³⁹ Centre for Epidemiology, Division of Population Health, Health Services Research & Primary Care, The University of Manchester, Manchester, UK.
• ⁴⁰ School of Healthcare Sciences, Manchester Metropolitan University, Manchester, United Kingdom.
• ⁴¹ Division of Translational Brain Sciences, Department of Neurology, Bryan Alzheimer's Disease Research Center, and Center for Genomic and Computational Biology, Duke University Medical Center, Durham, NC, USA.
• ⁴² Psychiatry and Behavioral Sciences, Division of Medical Psychology, and Department of Neurology, Duke University Medical Center, Durham, NC, USA.
• ⁴³ William Harvey Research Institute, Queen Mary University of London, London, UK.
• ⁴⁴ Helix Inc., San Diego, CA, USA.
• ⁴⁵ Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada.
• ⁴⁶ 2nd Department of Psychiatry, National and Kapodistrian University of Athens Medical School, University General Hospital "ATTIKON", Athens, Greece.
• ⁴⁷ University Mental Health Research Institute, Athens, Greece.
• ⁴⁸ Neurobiology Research Institute, Theodor-Theohari Cozzika Foundation, Athens, Greece.
• ⁴⁹ Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
• ⁵⁰ Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
• ⁵¹ UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA.
• ⁵² Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
• ⁵³ Department of Psychology, Yale University, New Haven, CT, USA.
• ⁵⁴ Department of Psychology, Stanford University, Palo Alto, CA, USA.
• ⁵⁵ Robert and Beverly Lewis Center for Neuroimaging, University of Oregon, Eugene, OR, USA.
• ⁵⁶ 23andMe, Inc., Mountain View, CA, USA.
• ⁵⁷ Weill Cornell Psychiatry at NewYork-Presbyterian, Weill Cornell Medical Center, New York, NY, USA.
• ⁵⁸ Laboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC, USA.
• ⁵⁹ Clinical and Translational Neuroscience Branch, Intramural Research Program, National Institute of Mental Health, National Institute of Health, Bethesda, MD, USA.
• ⁶⁰ Lieber Institute for Brain Development, Johns Hopkins University Medical Campus, Baltimore, MD, USA.
• ⁶¹ Neuroimaging, Cognition & Genomics (NICOG) Centre, School of Psychology and Discipline of Biochemistry, National University of Ireland, Galway, Ireland.
• ⁶² Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.
• ⁶³ Division of Neuroscience and Experimental Psychology/School of Biological Sciences, Faculty of Biology Medicine and Health, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, University of Manchester, Manchester, UK.
• ⁶⁴ Department of Psychiatry and Behavioral Sciences, Faculty of Medicine, University of Crete, Heraklion, Crete, GR, Greece.
• ⁶⁵ Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, Finland.
• ⁶⁶ Institute for Behavioral Genetics, University of Colorado, Boulder, CO, USA.
• ⁶⁷ Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
• ⁶⁸ Division of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY, USA. [email protected].
• ⁶⁹ Institute for Behavioral Science, Feinstein Institutes for Medical Research, Manhasset, NY, USA. [email protected].
• ⁷⁰ Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA. [email protected].