SARS-CoV-2 Related Ischemic Colitis in an Adolescent With Trisomy 21: Diagnostic Pitfalls and Considerations

Pediatr Dev Pathol. 2021 Sep-Oct;24(5):445-449. doi: 10.1177/10935266211015666. Epub 2021 May 28.

Abstract

Millions of patients seek medical attention for diarrhea, vomiting, nausea, and abdominal pain. In the current environment, it is important to recognize that these symptoms may be the only manifestation or may precede more serious systemic complications of COVID-19. Herein, we describe the first case of ischemic colitis (IC) in a young adult who presented with diarrhea and highlight the laboratory pitfalls for patients with COVID-19 presenting with gastrointestinal (GI) symptoms.

Keywords: COVID-19; GI; immunohistochemistry; microscopy; pediatric; surg path.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • COVID-19 / diagnosis
  • COVID-19 / virology*
  • Colitis, Ischemic / complications
  • Colitis, Ischemic / diagnosis*
  • Colitis, Ischemic / physiopathology
  • Diarrhea / complications
  • Diarrhea / virology
  • Down Syndrome / diagnosis
  • Down Syndrome / physiopathology*
  • Down Syndrome / virology
  • Gastrointestinal Diseases / complications
  • Gastrointestinal Diseases / diagnosis*
  • Gastrointestinal Diseases / virology
  • Humans
  • Male
  • SARS-CoV-2 / pathogenicity*