Optical Coherence Tomography in Acute Coronary Syndromes

Keyvan Karimi Galougahi; Evan Shlofmitz; Allen Jeremias; Gregory Petrossian; Gary S Mintz; Akiko Maehara; Richard Shlofmitz; Ziad A Ali

doi:10.1016/j.iccl.2021.03.004

Optical Coherence Tomography in Acute Coronary Syndromes

Interv Cardiol Clin. 2021 Jul;10(3):323-332. doi: 10.1016/j.iccl.2021.03.004.

Authors

Keyvan Karimi Galougahi¹, Evan Shlofmitz², Allen Jeremias², Gregory Petrossian², Gary S Mintz³, Akiko Maehara⁴, Richard Shlofmitz², Ziad A Ali⁵

Affiliations

¹ Royal Prince Alfred Hospital, Sydney, Australia; University of Sydney, Sydney, Australia; Heart Research Institute, 7 Eliza Street, Newtown, NSW 2042, Australia.
² The Heart Center, St Francis Hospital, 100 Port Washington Blvd, Flower Hill, NY 11576, USA.
³ Cardiovascular Research Foundation, 1700 Broadway, 9th Floor, New York, NY 10019, USA.
⁴ The Heart Center, St Francis Hospital, 100 Port Washington Blvd, Flower Hill, NY 11576, USA; Cardiovascular Research Foundation, 1700 Broadway, 9th Floor, New York, NY 10019, USA; New York-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY, USA.
⁵ The Heart Center, St Francis Hospital, 100 Port Washington Blvd, Flower Hill, NY 11576, USA; Cardiovascular Research Foundation, 1700 Broadway, 9th Floor, New York, NY 10019, USA; New York-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY, USA. Electronic address: [email protected].

PMID: 34053619
DOI: 10.1016/j.iccl.2021.03.004

Abstract

Advances in intravascular imaging have enabled assessment of the underlying plaque morphology in acute coronary syndromes, which allows for the initiation of individualized therapy. The atherothrombotic substrates for acute coronary syndromes consist of plaque rupture, erosion, and calcified nodule, whereas spontaneous coronary artery dissection, coronary artery spasm, and coronary embolism constitute rarer nonatherothrombotic etiologies. This review provides a brief overview of the data from clinical studies that have used intravascular optical coherence tomography to assess the culprit plaque morphology. We discuss the usefulness of intravascular imaging for effective treatment of patients presenting with acute coronary syndromes by percutaneous coronary intervention.

Keywords: Acute coronary syndromes; Intravascular ultrasound; Myocardial infarction; Optical coherence tomography; Percutaneous coronary intervention.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Acute Coronary Syndrome* / diagnosis
Humans
Percutaneous Coronary Intervention*
Plaque, Atherosclerotic* / diagnostic imaging
Rupture, Spontaneous
Tomography, Optical Coherence