Management problems in patients with pancreatic cancer from a surgeon's perspective

Semin Oncol. 2021 Feb;48(1):76-83. doi: 10.1053/j.seminoncol.2021.02.008. Epub 2021 Apr 21.

Abstract

Pancreatic cancer is one of the most lethal gastrointestinal tumor entities. Surgery is the only chance for cure; however, only a minority of patients can be offered this option. Due to the anatomic location of the gland, tumor-related problems and complications affecting the surrounding structures are common, leading to biliary and gastric outlet obstruction as well as portal vein thrombosis. This review article summarizes the management of pancreatic cancer-related problems from a surgical point of view. We further describe surgical treatment options in unresectable, metastasized and recurring pancreatic cancer, highlighting potential resection of oligometastatic disease in selected settings.

Keywords: Palliative treatment; Pancreatic cancer; Surgery.

Publication types

  • Review

MeSH terms

  • Gastric Outlet Obstruction* / complications
  • Gastric Outlet Obstruction* / surgery
  • Humans
  • Palliative Care
  • Pancreatic Neoplasms* / complications
  • Pancreatic Neoplasms* / pathology
  • Pancreatic Neoplasms* / surgery
  • Surgeons*