The association of MHPG to dexamethasone suppression test status

Psychiatry Res. 1988 May;24(2):223-30. doi: 10.1016/0165-1781(88)90065-0.

Abstract

The results of the dexamethasone suppression test (DST) were compared to levels of 24-hour 3-methoxy-4-hydroxyphenylglycol (MHPG) in 60 patients with unipolar depression. DST nonsuppressors had significantly higher levels of MHPG than did DST suppressors. The possible implications of this finding are discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Depression / diagnosis
  • Depression / urine*
  • Dexamethasone*
  • Female
  • Glycols / urine*
  • Humans
  • Hydrocortisone / urine
  • Male
  • Methoxyhydroxyphenylglycol / urine*

Substances

  • Glycols
  • Methoxyhydroxyphenylglycol
  • Dexamethasone
  • Hydrocortisone