Prolonged erections following intracorporeal injection of medications to overcome impotence

Br J Urol. 1988 Aug;62(2):173-5. doi: 10.1111/j.1464-410x.1988.tb04301.x.

Abstract

We describe the management of 17 men who developed prolonged erections following the intracorporeal injection of vasoactive drugs (e.g. papaverine) for the treatment of erectile dysfunction. Twelve men who had psychogenic impotence developed prolonged erections following injection compared with 5 who had an organic aetiology. The aspiration of 20 to 50 ml of blood from the penis together with the intracorporeal injection of 1 to 2 mg metaraminol is an effective treatment of this complication.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Erectile Dysfunction / drug therapy*
  • Humans
  • Male
  • Metaraminol / therapeutic use
  • Middle Aged
  • Papaverine / adverse effects*
  • Papaverine / therapeutic use
  • Phenoxybenzamine / adverse effects
  • Phentolamine / adverse effects
  • Priapism / chemically induced*
  • Priapism / therapy

Substances

  • Phenoxybenzamine
  • Metaraminol
  • Papaverine
  • Phentolamine