False positive pharmacologic myocardial perfusion SPECT study in the setting of a left bundle branch block

Thuy D Nguyen; David Lin; Miguel Hernandez Pampaloni

doi:10.1097/MNM.0000000000001451

False positive pharmacologic myocardial perfusion SPECT study in the setting of a left bundle branch block

Nucl Med Commun. 2021 Nov 1;42(11):1288-1291. doi: 10.1097/MNM.0000000000001451.

Authors

Thuy D Nguyen¹, David Lin², Miguel Hernandez Pampaloni²

Affiliations

¹ Department of Medicine (Cardiovascular Division).
² Department of Radiology and Biomedical Imaging, University of California, San Francisco Medical Center, San Francisco, California, USA.

PMID: 34100795
DOI: 10.1097/MNM.0000000000001451

Abstract

We herein report a case of a false positive vasodilatory pharmacologic SPECT stress test in the setting of a left bundle branch block (LBBB). While this is more commonly seen with exercise stress testing, it can also occur with pharmacologic stress testing. In our SPECT exam, we illustrate the commonly mistaken septal/anteroseptal perfusion defects in those patients with a LBBB. PET stress testing may be more reliable for patients with LBBB.

Publication types

Case Reports

MeSH terms

Bundle-Branch Block* / diagnostic imaging
Bundle-Branch Block* / physiopathology
Exercise Test
False Positive Reactions
Humans
Myocardial Perfusion Imaging*
Tomography, Emission-Computed, Single-Photon*