Diffuse functional brain disconnection syndrome in critically ill patients with COVID-19

Carmine Iacovazzo; Maria Vargas; Enrico Tedeschi; Anna De Simone; Arturo Brunetti; Giuseppe Servillo

doi:10.1016/j.jiph.2021.05.011

Diffuse functional brain disconnection syndrome in critically ill patients with COVID-19

J Infect Public Health. 2021 Jul;14(7):906-909. doi: 10.1016/j.jiph.2021.05.011. Epub 2021 May 27.

Authors

Carmine Iacovazzo¹, Maria Vargas², Enrico Tedeschi³, Anna De Simone¹, Arturo Brunetti³, Giuseppe Servillo¹

Affiliations

¹ Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.
² Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy. Electronic address: [email protected].
³ Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.

Abstract

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is most closely related to severe respiratory syndrome; however, recent reports showed that it is capable of causing neurological disease. Here we report a case-series of 4 critically ill COVID-19 patients who recovered from pneumonia but showed serious neurological symptoms and eventually died.

Keywords: Brain; Brain damage; COVID-19; Disfunction.

Publication types

Case Reports

MeSH terms

Brain / diagnostic imaging
Brain Diseases*
COVID-19*
Critical Illness
Humans
SARS-CoV-2