Comparison of 18F-FDG, 68Ga-FAPI, and 68Ga-DOTATATE PET/CT in a Patient With Pancreatic Neuroendocrine Tumor

Clin Nucl Med. 2021 Sep 1;46(9):764-765. doi: 10.1097/RLU.0000000000003763.

Abstract

We present image findings of 18F-FDG, 68Ga-FAPI, and 68Ga-DOTATATE PET/CT in a 35-year-old woman with multiple metastases of pancreatic neuroendocrine tumor. The images of PET/CTs using 3 different tracers all showed multiple foci of increased activities in the liver and pancreas body, in which 68Ga-FAPI PET/CT displayed the highest tumor-to-liver ratios. However, 68Ga-DOTATATE PET/CT detected more small metastatic lymph node and bone metastases, which were missed by both FDG and FAPI PET/CT.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Liver Neoplasms*
  • Organometallic Compounds
  • Pancreatic Neoplasms* / diagnostic imaging
  • Positron Emission Tomography Computed Tomography
  • Quinolines

Substances

  • 68Ga-FAPI
  • Organometallic Compounds
  • Quinolines
  • Fluorodeoxyglucose F18
  • gallium Ga 68 dotatate